Assuntos
Traumatismos do Braço/complicações , Artrite Psoriásica/complicações , Doenças da Unha/complicações , Traumatismos dos Nervos Periféricos/complicações , Artrite Psoriásica/patologia , Artrite Psoriásica/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças da Unha/patologia , Doenças da Unha/fisiopatologia , Remissão EspontâneaAssuntos
Eritema Nodoso/etiologia , Transplante de Rim/efeitos adversos , Hanseníase Virchowiana/etiologia , Adulto , Eritema Nodoso/tratamento farmacológico , Eritema Nodoso/patologia , Humanos , Hansenostáticos/uso terapêutico , Hanseníase Virchowiana/tratamento farmacológico , Hanseníase Virchowiana/patologia , Masculino , Prognóstico , TransplantadosRESUMO
BACKGROUND: In recent studies, it has been documented that the eosinophil cells play active role in many kinds of inflammatory disorders. Measurements of the mediators released by eosinophils and cell counts in serum and skin have provided some evidence indicating the role of eosinophils in psoriasis. OBJECTIVE: To evaluate the blood eosinophil cell count in patients with erythrodermic psoriasis and generalized pustular psoriasis. METHODS: In this study, 48 patients with histopathologically proven psoriasis (33 with erythrodermic, 15 with generalized pustular); 43 patients with maculopapular, erythematous, or bullous drug eruption with widespread involvement; and 51 patients with basal cell carcinoma were included. These three groups were compared with each other in terms of their absolute eosinophil cell counts and percentage of eosinophils. RESULTS: Forty-one point seven per cent of patients with psoriasis had peripheral blood eosinophilia compared with 58.1% of the patients with drug eruption and 11.8% of patients with basal cell carcinoma. The percentage of patients with eosinophilia both in patients suffering from psoriasis and drug eruption were significantly increased compared with the patients with basal cell carcinoma (P < 0.001). The absolute median eosinophil cell counts both in patients with psoriasis and drug eruption were also significantly differed from patients with basal cell carcinoma (259.2, 439.1 and 183.1, respectively; P < 0.001) CONCLUSIONS: Peripheral blood eosinophilia seems to be associated with severe forms of psoriasis. This finding may suggest that the eosinophils have significant roles in the pathogenesis of these types of psoriasis.
Assuntos
Eosinofilia/imunologia , Eosinófilos , Psoríase/imunologia , Análise de Variância , Contagem de Células Sanguíneas , Carcinoma Basocelular/imunologia , Distribuição de Qui-Quadrado , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Cutâneas/imunologia , Estatísticas não ParamétricasAssuntos
Mycobacterium tuberculosis , Análise de Sequência de DNA/métodos , Tuberculose Cutânea/diagnóstico , Idoso de 80 Anos ou mais , Antituberculosos/uso terapêutico , Diagnóstico Diferencial , Feminino , Humanos , Mycobacterium tuberculosis/efeitos dos fármacos , Mycobacterium tuberculosis/genética , Mycobacterium tuberculosis/isolamento & purificação , Tuberculose Cutânea/tratamento farmacológico , Tuberculose Cutânea/microbiologiaRESUMO
Atypical presentations of molluscum contagiosum (MC) infection can be expected in renal transplant recipients, as a result of long-term immunosuppression. However, giant MC has rarely been reported in this population. We present a 28-year-old female renal transplant recipient receiving immunosuppressive therapy who developed multiple giant MC lesions on her axillary folds. The lesions were treated successfully with curettage and electrocauterization.
